angiotensin ii , human — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7040	Angiotensin II human	DRVYIHPF,Angiotensin II,Hypertensin II,Ang II	Apoptosis , RAAS
	Angiotensin II human (Ang II) is a biologically active peptide, a vasoconstrictor. Angiotensin II interacts with AT1R and AT2R to regulate blood pressure, stimulate sympathetic nerves, and increase aldosterone biosynthes...		Apoptosis , RAAS
T8560	Angiotensin II human acetate	Ang II acetate,DRVYIHPF acetate,Angiotensin II acetate	Apoptosis , RAAS
	Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.		Apoptosis , RAAS
TP1609	Angiotensin II (1-4), human
	Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure. Angiotensin also potentiates the release of norepinephrine by a direct action on po...
TP1522	Angiotensin II (5-8), human
	Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II
T5824	Angiotensin II (3-8), human	Angiotensin IV	RAAS
	Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.		RAAS
T10323	Angiotensin II (3-8), human TFA		RAAS
	Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.		RAAS
TP1661	Angiotensin II (1-4), human TFA
	Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.
T74142	Angiotensin II human TFA
	Angiotensin II human TFA, a potent vasoconstrictor within the renin/angiotensin system, plays a pivotal role in human blood pressure regulation primarily through interactions with the G-protein-coupled receptors Angioten...
T7577	Angiotensin III, human, mouse	Angiotensin III, human, mouse(3TFA)	RAAS
	Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA))(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).		RAAS
T2531L	Eprosartan	KF-108566J free base,Teveten	RAAS
	Eprosartan (SKF-108566J free base) is a selective and competitive nonpeptide angiotensin II receptor antagonist with high affinity for AT1 receptor subtypes and can be used as an antihypertensive agent.Eprosartan has an ...		RAAS
TP1295	Angiotensin I (human, mouse, rat)	Angiotensin 1 Human	Others
	Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE).Angiotensin is a peptide hormone that causes vasoconstriction and an in...		Others
T37825	CAY10434		P450
	CAY10434 is an active inhibitor of CYP4A hydroxylase with an IC50 value of 8.8 nM in human kidney microsomal test. The maximum contractile value (Emax) of CAY 10434 was 6764 mg in improving the contractile process of ang...		P450
T3461	Losartan Carboxylic Acid	EXP-3174,E-3174	RAAS
	Losartan Carboxylic Acid (E-3174) a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. Losartan Carboxylic Acid , a metabolite of losartan, is more potent than l...		RAAS
T35725	4-hydroxy Valsartan
	4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan . It reduces platelet aggregation induced by epinephrine and collagen but not ADP in human whole blood.
T35865	Telmisartan Acyl-β-D-Glucuronide
	Telmisartan acyl-β-D-glucuronide is a major metabolite of the angiotensin II receptor antagonist telmisartan . It does not bind human serum albumin and is cleared from rat plasma with a clearance rate of 180 ml/min/kg fo...
T81229	Safflor yellow B
	Safflor Yellow B mitigates angiotensin II-induced injury in human umbilical vein cells by modulating Bcl-2/p22(phox) expression and demonstrates neuroprotective effects [1].
T36209	15-keto Prostaglandin A1	15-keto Prostaglandin A1
	Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. 15-keto PGA1 is a metabolite of PGA1, produced by 15-hydroxy PG dehydrogenase. It can be produced from PGA1 ...
T63295	AT2R antagonist 1
	AT2R antagonist 1 is a highly selective and potent AT2R (angiotensin II AT2 receptor) ligand.AT2R antagonist 1 has a high affinity for AT2R affinity (Ki: 29 nM).AT2R antagonist 1 inhibits common drug metabolizing CYP enz...